Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.40 |
| ▸ | PIM1 | P11309 | 5/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PKLR | P30613 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | GALNT2 | Q10471 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phelligridin J SCHEMBL31399403 | 0.76 | PKLR (0.45) | AKR1B1CSNK2A1PIM1CSNK2A2CSNK2B | |
| SCHEMBL7382104 | 0.76 | PIM1 (0.50) | PIM1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL9424948 | 0.75 | PIM1 (0.55) | AKR1B1CSNK2A1PIM1CSNK2A2CSNK2B | |
| SCHEMBL175987 | 0.74 | ALDH1A1 (0.59) | CSNK2A1PIM1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL5563883 | 0.70 | AKR1B1 (0.65) | AKR1B1CSNK2A1PIM1CSNK2A2CSNK2B | |
| SCHEMBL14402284 | 0.70 | ALDH1A1 (0.46) | CSNK2A1PIM1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL5554955 | 0.69 | PIM1 (0.43) | AKR1B1CSNK2A1PIM1CSNK2A2CSNK2B | |
| Formic Acid SCHEMBL11853384 | 0.69 | ALDH1A1 (0.55) | CSNK2A1PIM1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL6945650 | 0.66 | MEN1 (0.48) | PIM1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL2707336 | 0.66 | TDP1 (0.47) | AKR1B1KDM4EKMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5232918-A | Bactericides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |