Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.49 |
| ▸ | PRKX | P51817 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MYLK | Q15746 | 3/20 | 0.43 |
| ▸ | PRKACA | P17612 | 3/20 | 0.43 |
| ▸ | PRKACG | P22612 | 3/20 | 0.43 |
| ▸ | PRKACB | P22694 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31399681 | 0.91 | ROCK2 (0.59) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399713 | 0.79 | ROCK2 (0.41) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399689 | 0.78 | TGM2 (0.44) | TSHRLMNAKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL7045951 | 0.77 | ROCK2 (0.67) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399729 | 0.76 | TGM2 (0.46) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399766 | 0.76 | ROCK2 (0.63) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399751 | 0.76 | ROCK2 (0.59) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399726 | 0.75 | TRPV4 (0.67) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399750 | 0.73 | TGM2 (0.64) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL7049151 | 0.72 | ROCK2 (0.71) | ROCK2ROCK1PRKCEPRKCDPRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739672-A1 | NEW COMPOUNDS | Aston University (GB) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008626-A1 | NEW COMPOUNDS | ASTON UNIVERSITY (GB) | 2025-01-09 | — | — | WO | disclosed |