Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629679 | 0.89 | TSHR (0.55) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL13176891 | 0.89 | TSHR (0.60) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL1330407 | 0.89 | TSHR (0.55) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL11095264 | 0.87 | ALOX15 (0.58) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL12950315 | 0.86 | TSHR (0.52) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL29878242 | 0.86 | TSHR (0.52) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL13941262 | 0.84 | TSHR (0.50) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL11098649 | 0.82 | TSHR (0.49) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL3921406 | 0.82 | ALDH1A1 (0.49) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL27801299 | 0.82 | ALDH1A1 (0.49) | TSHRCYP3A4ALDH1A1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118652912-A | Preparation and application of nitroreductase recombinant plasmid | 中国人民解放军军事科学院防化研究院 | 2024-09-17 | — | — | CN | claimed |
| EP-1844189-B1 | Method for preparing a sampling swab | SMITHS DETECTION INC (CA) | 2020-10-28 | — | — | EP | claimed |
| US-20200094301-A1 | Heat-Enhanced Treatment Of Energetic Compounds In Contaminated Soil, Sediment And/Or Water | CDM SMITH INC. | 2020-03-26 | — | — | US | claimed |
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| US-10119953-B1 | Metal chalcogenide quantum dots for the detection of nitroaromatic chemicals | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2018-11-06 | — | — | US | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| US-9546247-B2 | Explosive detection polymer comprising functionalized polyamine polymers and methods of using the same | UNIVERSITY OF CONNECTICUT (US) | 2017-01-17 | — | — | US | claimed |
| US-9365441-B2 | Product and method for treatment of soil and groundwater contaminated with pollutants that can be anaerobically bioremediated | BORDEN ROBERT C (US) | 2016-06-14 | — | — | US | claimed |
| US-20150329390-A1 | PRODUCT AND METHOD FOR TREATMENT OF SOIL AND GROUNDWATER CONTAMINATED WITH POLLUTANTS THAT CAN BE ANAEROBICALLY BIOREMEDIATED | BORDEN ROBERT C (US) | 2015-11-19 | — | — | US | claimed |
| US-20150056711-A1 | Explosive Detection Polymer Comprising Functionalized Polyamine Polymers and Methods of Using the Same | UNIVERSITY OF CONNECTICUT (US) | 2015-02-26 | — | — | US | claimed |
| US-20090240033-A1 | AFFINITY MATRIX LIBRARY AND ITS USE | LI RONGXIU | 2009-09-24 | — | — | US | claimed |
| EP-1844189-A2 | SAMPLING SWAB | Smiths Detection Inc. (CA) | 2007-10-17 | — | — | EP | claimed |
| WO-2007066240-A2 | SAMPLING SWAB | SMITHS DETECTION INC. (US) | 2007-06-14 | — | — | WO | claimed |
| US-20060192098-A1 | Sampling swab | SMITHS DETECTION INC. | 2006-08-31 | — | — | US | claimed |
| US-20050288616-A1 | Sampling swab | SMITHS DETECTION, INC. | 2005-12-29 | — | — | US | claimed |
| US-6719902-B1 | TREATING AN ENVIRONMENTAL SITE WITH AN EFFECTIVE AMOUNT OF A COMPOSITION COMPRISING ONE OR MORE HYDROGENOTROPHIC BACTERIA AND ZERO-VALENT IRON | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2004-04-13 | — | — | US | claimed |
| US-6477907-B1 | Detection of explosives in soils | SANDIA CORPORATION | 2002-11-12 | — | — | US | claimed |
| WO-1998049106-A1 | FE(O)-BASED BIOREMEDIATION OF AQUIFERS CONTAMINATED WITH MIXED WASTES | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-11-05 | — | — | WO | claimed |
| US-4451681-A | Methods of preparing pentanitrotoluene | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1984-05-29 | — | — | US | claimed |
| US-4248798-A | New method for preparing pentanitroaniline and triaminotrinitrobenzenes from trinitrotoluene | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1981-02-03 | — | — | US | claimed |