Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1330407 | 1.00 | TSHR (0.55) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL314000 | 0.89 | TSHR (0.61) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL259813 | 0.83 | TSHR (0.60) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL13176891 | 0.83 | TSHR (0.60) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL11095264 | 0.82 | ALOX15 (0.58) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL938651 | 0.82 | GPR35 (0.61) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL27801299 | 0.81 | ALDH1A1 (0.49) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL4748374 | 0.80 | TSHR (0.47) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL5203487 | 0.80 | CYP1A2 (0.52) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL3611223 | 0.80 | TSHR (0.47) | TSHRCYP3A4ALDH1A1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118652912-A | Preparation and application of nitroreductase recombinant plasmid | 中国人民解放军军事科学院防化研究院 | 2024-09-17 | — | — | CN | claimed |
| CN-118703370-A | Preparation and application methods of TNT and intermediate toxic byproduct degrading bacterial agent thereof | 中国人民解放军军事科学院防化研究院 | 2024-09-27 | — | — | CN | disclosed |
| CN-118652912-A | Preparation and application of nitroreductase recombinant plasmid | 中国人民解放军军事科学院防化研究院 | 2024-09-17 | — | — | CN | disclosed |
| US-9856499-B2 | Long chain organic acid bioproduction | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-01-02 | — | — | US | disclosed |
| US-20150044743-A1 | LONG CHAIN ORGANIC ACID BIOPRODUCTION | WILLIAM MARSH RICE UNIVERSITY | 2015-02-12 | — | — | US | disclosed |
| US-8569451-B2 | Affinity material | BIOTAGE AB (SE) | 2013-10-29 | — | — | US | disclosed |
| EP-2419452-B1 | AFFINITY MATERIAL | BIOTAGE AB (SE) | 2013-08-21 | — | — | EP | disclosed |
| WO-2013096665-A1 | LONG CHAIN ORGANIC ACID BIOPRODUCTION | WILLIAM MARSH RICE UNIVERSITY (US) | 2013-06-27 | — | — | WO | disclosed |
| US-20120095165-A1 | AFFINITY MATERIAL | BIOTAGE AB (SE) | 2012-04-19 | — | — | US | disclosed |
| EP-2419452-A1 | AFFINITY MATERIAL | Biotage AB (SE) | 2012-02-22 | — | — | EP | disclosed |
| US-6475387-B1 | Microbiological method for eliminating a nitroaromatic compound | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2002-11-05 | — | — | US | disclosed |
| US-6066772-A | ADMIXING THE EXPLOSIVES CONTAMINATED SOIL WITH MICROORGANISM AND CARBON SOURCE UNDER ANAEROBIC CONDITIONS TO PRODUCE AN ANAEROBIC BIOREMEDIATION PRODUCT, THEN MIXING IN COMPOSTABLE MATERIAL AND AEROBICALLY BIOREMEDIATING TO HUMIC COMPOUNDS | WASTE MANAGEMENT, INC. (US) | 2000-05-23 | — | — | US | disclosed |
| US-6051420-A | Method for the decontamination of soil containing solid organic explosives therein | BECHTEL BWXT IDAHO, LLC (US) | 2000-04-18 | — | — | US | disclosed |
| WO-1999010298-A1 | TREATMENT OF TNT-CONTAMINATED SOIL | WASTE MANAGEMENT, INC. (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1998053105-A1 | METHOD FOR THE DECONTAMINATION OF SOIL CONTAINING SOLID ORGANIC EXPLOSIVES THEREIN | LOCKHEED MARTIN IDAHO TECHNOLOGIES COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |
| WO-1995028475-A2 | BIOLOGICAL ISOLATES FOR DEGRADING NITROAROMATICS AND NITRAMINES IN WATER AND SOILS | IDAHO RESEARCH FOUNDATION, INC. (US) | 1995-10-26 | — | — | WO | disclosed |
| US-5455173-A | Biologically pure culture of strain of Clostridium bifermentans | IDAHO RESEARCH FOUNDATION, INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-4549007-A | REACTION INJECTION MOLDING OF POLYURETHANES-POLYUREAS | GAF CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
| US-4523004-A | 1,4-BUTANEDIOL AND MONOSUBSTITUTED TOLUENE DIAMINE | GAF CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| EP-0102203-A1 | Diamine/diol chain extender blends for RIM process | GAF CORPORATION (US) | 1984-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095165-A1 | AFFINITY MATERIAL | FCGR3B, FCGR2A, FCGR1A | TSHR 2348/4885CYP3A4 4799/4885ALDH1A1 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.