Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314000 | 0.87 | TSHR (0.61) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL1330407 | 0.82 | TSHR (0.55) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL13176891 | 0.82 | TSHR (0.60) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL11113072 | 0.82 | GPR35 (0.67) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL629679 | 0.82 | TSHR (0.55) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL29577133 | 0.80 | GPR35 (0.66) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL3132904 | 0.80 | GPR35 (0.66) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL14155059 | 0.79 | ALOX15 (0.64) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL27801299 | 0.79 | ALDH1A1 (0.49) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL8059114 | 0.79 | GPR35 (0.61) | ALOX15MAPK1HSD17B10L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |