SCHEMBL31404126

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O

nearest known ligand 0.59

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	SLC6A2	P23975	2/20	0.57

▸	OPRM1	P35372	4/20	0.52

▸	OPRD1	P41143	4/20	0.52

▸	FCGRT	P55899	3/20	0.50

▸	OPRK1	P41145	2/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28210612	0.95	OPRM1 (0.55)	SLC6A2OPRM1OPRD1OPRK1
SCHEMBL28846618	0.95	OPRM1 (0.55)	SLC6A2OPRM1OPRD1OPRK1
SCHEMBL30163263	0.95	OPRM1 (0.55)	SLC6A2OPRM1OPRD1OPRK1
SCHEMBL15130591	0.95	OPRM1 (0.55)	SLC6A2OPRM1OPRD1OPRK1
SCHEMBL14549930	0.95	OPRM1 (0.55)	SLC6A2OPRM1OPRD1OPRK1
SCHEMBL30163405	0.95	OPRM1 (0.56)	SLC6A2OPRM1OPRD1OPRK1
SCHEMBL30163248	0.94	OPRM1 (0.55)	SLC6A2OPRM1OPRD1FCGRTOPRK1
SCHEMBL30353299	0.94	SLC6A2 (0.55)	SLC6A2OPRM1OPRD1FCGRTOPRK1
SCHEMBL29597272	0.93	OPRM1 (0.55)	SLC6A2OPRM1OPRD1OPRK1
SCHEMBL14549924	0.92	KEAP1 (0.56)	SLC6A2OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025075499-A1	REDUCING DOPAMINE FEED-BACK INHIBITION IN DOPAMINERGIC CELLS BY TADALAFIL.	UNIVERSITEIT VAN AMSTERDAM (NL)	2025-04-10	—	—	WO	disclosed