SCHEMBL31405487

SCHEMBL31405487

Cc1cc(C)c(N(c2cccc(Br)c2)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
MAPK1 P28482 1/20 0.48
RAPGEF4 Q8WZA2 2/20 0.47
MTNR1A P48039 2/20 0.35
MTNR1B P49286 2/20 0.35
TAAR1 Q96RJ0 1/20 0.34
MAOB P27338 4/20 0.34
HTR7 P34969 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765461 0.86 ACHE (0.38) ALDH1A1MAPK1RAPGEF4
SCHEMBL3366623 0.79 ALDH1A1 (0.46) ALDH1A1MAPK1MTNR1AMTNR1BTAAR1
SCHEMBL5573680 0.78 ALDH1A1 (0.50) ALDH1A1MAPK1RAPGEF4MTNR1AMTNR1B
SCHEMBL12084121 0.78 ALDH1A1 (0.61) ALDH1A1MAPK1RAPGEF4MTNR1AMTNR1B
SCHEMBL31405486 0.78 RAPGEF4 (0.47) ALDH1A1MAPK1RAPGEF4MEN1NPC1
SCHEMBL26233607 0.78 CETP (0.36) ALDH1A1MAPK1RAPGEF4MTNR1AMTNR1B
SCHEMBL22550359 0.77 CYP1A2 (0.41) ALDH1A1MAPK1KDM4EMEN1MAPT
SCHEMBL13949243 0.77 ALDH1A1 (0.37) ALDH1A1RAPGEF4KDM4EMAPT
SCHEMBL13878214 0.77 PDK2 (0.33) ALDH1A1MAPK1RAPGEF4
SCHEMBL8765439 0.77 ALDH1A1 (0.44) ALDH1A1MAPK1MTNR1AMTNR1BTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250089563-A1 LIGHT-EMITTING DEVICE INCLUDING AMINE-CONTAINING COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE AMINE-CONTAINING COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2025-03-13 US disclosed
CN-119569760-A Light-emitting device including amine-containing compound, electronic apparatus and electronic device including light-emitting device, and amine-containing compound 三星显示有限公司 2025-03-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250089563-A1 LIGHT-EMITTING DEVICE INCLUDING AMINE-CONTAINING COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE AMINE-CONTAINING COMPOUND TAAR1, AADAT, AAAS ALDH1A1 24/4885MAPK1 1851/4885RAPGEF4 3705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.