Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31406215 | 0.83 | HRH3 (0.39) | — | |
| SCHEMBL31406210 | 0.79 | HTR2A (0.39) | LMNAHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL757194 | 0.79 | LMNA (0.46) | LMNAHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL31406213 | 0.78 | HTR2C (0.54) | HTR2AHTR2CHTR2B | |
| SCHEMBL31406193 | 0.76 | SLC6A3 (0.45) | KMT2ATSHR | |
| SCHEMBL8102189 | 0.70 | L3MBTL1 (0.47) | LMNAHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL8102186 | 0.70 | L3MBTL1 (0.47) | LMNAHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL6393978 | 0.67 | ALDH1A1 (0.50) | LMNAHTR2BMAPTALDH1A1HPGD | |
| SCHEMBL318343 | 0.67 | HTR2C (0.51) | HTR2AHTR2CHTR2BSLC9A1DDB1 | |
| SCHEMBL765244 | 0.67 | HTR2C (0.51) | HTR2AHTR2CHTR2BSLC9A1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025014719-A2 | TROPANE COMPOUNDS FOR TREATING BRAIN DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-16 | — | — | WO | disclosed |