Sugi Predict

Sugi Predict / Compounds / SCHEMBL1671676

SCHEMBL1671676

SCHEMBL1671676

O=C(O)[C@H](O)c1ccccc1F

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 4/20 0.63
▸ CES1 P23141 4/20 0.63
▸ LMNA P02545 3/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ GAA P10253 1/20 0.47
▸ CNR2 P34972 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ KMT2A Q03164 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ PTPN1 P18031 1/20 0.41
▸ PTPN7 P35236 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ ESR2 Q92731 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ IDO1 P14902 1/20 0.40
▸ TDO2 P48775 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KCNN4 O15554 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL469655 1.00 CES2 (0.63) CES2CES1LMNAMAPK1GAA
SCHEMBL30670483 1.00 CES2 (0.63) CES2CES1LMNAMAPK1GAA
SCHEMBL11354965 1.00 CES2 (0.63) CES2CES1LMNAMAPK1GAA
SCHEMBL10563843 0.85 CES2 (0.49) CES2CES1LMNAMAPK1GAA
Benzylic Acid SCHEMBL1670871 0.85 CES2 (0.49) CES2CES1LMNAMAPK1GAA
SCHEMBL9103702 0.84 CES2 (0.47) CES2CES1LMNAMAPK1GAA
SCHEMBL275598 0.84 LMNA (0.64) CES2CES1LMNAMAPK1KMT2A
SCHEMBL23972274 0.83 CES2 (0.66) CES2CES1LMNAMAPK1GAA
SCHEMBL31407017 0.83 CES2 (0.66) CES2CES1LMNAMAPK1GAA
SCHEMBL31407025 0.83 CES2 (0.66) CES2CES1LMNAMAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113355367-B Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid 浙江工业大学 2024-03-26 — — CN claimed
CN-114733578-B Vulcanizing liquid and preparation method and application thereof 中国石油化工股份有限公司 2024-01-05 — — CN claimed
US-20220325035-A1 POLYESTER, POLYESTERAMIDE, AND POLYAMIDE COMPOSITIONS IYER ANANTH V (US) 2022-10-13 — — US claimed
CN-114733578-A Vulcanizing liquid and preparation method and application thereof 中国石油化工股份有限公司 2022-07-12 — — CN claimed
CN-113355299-B Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid 浙江工业大学 2022-05-24 — — CN claimed
CN-113980580-B Alkali etching polishing method for monocrystalline silicon wafer 绍兴拓邦新能源股份有限公司 2022-04-08 — — CN claimed
CN-113980580-A Alkali etching polishing method for monocrystalline silicon wafer 绍兴拓邦电子科技有限公司 2022-01-28 — — CN claimed
CN-113355299-A Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid 浙江工业大学 2021-09-07 — — CN claimed
CN-113355367-A Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid 浙江工业大学 2021-09-07 — — CN claimed
CN-108410831-B Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid 浙江工业大学 2021-07-27 — — CN claimed
EP-2485678-A1 COFERONS AND METHODS OF MAKING AND USING THEM Cornell University (US) 2012-08-15 — — EP claimed
WO-2011043817-A1 COFERONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2011-04-14 — — WO claimed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 — — WO disclosed
CN-113355367-B Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid 浙江工业大学 2024-03-26 — — CN disclosed
CN-114733578-B Vulcanizing liquid and preparation method and application thereof 中国石油化工股份有限公司 2024-01-05 — — CN disclosed
US-20230159538-A1 PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS GLOBAL BLOOD THERAPEUTICS, INC. 2023-05-25 — — US disclosed
EP-0007204-B1 PHENETHANOLAMINES, THEIR FORMULATIONS, USE AND PREPARATION ELI LILLY AND COMPANY (US) 1982-11-24 — — EP disclosed
EP-0048037-A1 Optically active 1-alkyl-3-(4-substituted-phenyl)-propylamines ELI LILLY AND COMPANY (US) 1982-03-24 — — EP disclosed
EP-0007204-A1 Phenethanolamines, their formulations, use and preparation ELI LILLY AND COMPANY (US) 1980-01-23 — — EP disclosed
EP-0006766-A1 Phenethanolamines, their formulations, use and preparation ELI LILLY AND COMPANY (US) 1980-01-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159538-A1 PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS PDK1, PDK2, PKM CES2 4622/4885CES1 3293/4885LMNA 853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.