Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407266 | 0.83 | HTR2C (0.32) | HTR2CSLC6A4HTR2A | |
| SCHEMBL31407260 | 0.77 | GSK3B (0.40) | GPR119HTR2CSLC6A4KDM4DHTR2A | |
| SCHEMBL31407263 | 0.75 | SSTR4 (0.41) | GPR119CACNA1GCACNA1BCACNA1CHTR2C | |
| SCHEMBL31407151 | 0.75 | SSTR4 (0.41) | GPR119CACNA1GCACNA1BCACNA1CHTR2C | |
| SCHEMBL31407169 | 0.74 | HTR2C (0.37) | GPR119CACNA1GCACNA1BCACNA1CHTR2C | |
| SCHEMBL31407201 | 0.73 | GPR119 (0.41) | GPR119HTR2CSLC6A4KDM4DHTR2A | |
| Hydrochloric Acid SCHEMBL31407165 | 0.72 | GSK3B (0.37) | GPR119HTR2CSLC6A4KDM4DHTR2A | |
| SCHEMBL31407270 | 0.72 | GPR119 (0.40) | GPR119HTR2CSLC6A4HTR2AMAPT | |
| SCHEMBL31407220 | 0.72 | GPR119 (0.40) | GPR119HTR2CSLC6A4HTR2AMAPT | |
| SCHEMBL31407207 | 0.71 | ALDH1A1 (0.43) | GPR119CACNA1GCACNA1BCACNA1CHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |