Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407151 | 1.00 | SSTR4 (0.41) | SSTR4CACNA1GCACNA1BCACNA1CPOLB | |
| SCHEMBL17018461 | 0.87 | SSTR4 (0.42) | SSTR4POLBSLC6A4GPR119SLC6A2 | |
| SCHEMBL31407169 | 0.85 | HTR2C (0.37) | SSTR4CACNA1GCACNA1BCACNA1CPOLB | |
| SCHEMBL15261600 | 0.82 | HTR2C (0.43) | SSTR4SLC6A4HTR2CRIPK1SOS1 | |
| SCHEMBL6501824 | 0.82 | CACNA1G (0.41) | SSTR4CACNA1GCACNA1BCACNA1CPOLB | |
| SCHEMBL31407207 | 0.82 | ALDH1A1 (0.43) | CACNA1GCACNA1BCACNA1CPOLBSLC6A4 | |
| SCHEMBL31407201 | 0.81 | GPR119 (0.41) | SSTR4SLC6A4HTR2CGPR119HTR2A | |
| SCHEMBL31407270 | 0.80 | GPR119 (0.40) | SLC6A4HTR2CGPR119HTR2AMAPT | |
| SCHEMBL31407220 | 0.80 | GPR119 (0.40) | SLC6A4HTR2CGPR119HTR2AMAPT | |
| SCHEMBL29687220 | 0.79 | CACNA1G (0.36) | SSTR4CACNA1GCACNA1BCACNA1CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |