Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407263 | 0.81 | SSTR4 (0.41) | GPR119HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL31407151 | 0.81 | SSTR4 (0.41) | GPR119HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL31407169 | 0.80 | HTR2C (0.37) | GPR119HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL31407260 | 0.78 | GSK3B (0.40) | GPR119HTR2CSLC6A4HTR2AKDM4D | |
| SCHEMBL31407270 | 0.77 | GPR119 (0.40) | GPR119HTR2CSLC6A4HTR2A | |
| SCHEMBL31407220 | 0.77 | GPR119 (0.40) | GPR119HTR2CSLC6A4HTR2A | |
| SCHEMBL31407207 | 0.77 | ALDH1A1 (0.43) | GPR119HTR2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL31407165 | 0.75 | GSK3B (0.37) | GPR119HTR2CSLC6A4HTR2AKDM4D | |
| SCHEMBL29687220 | 0.74 | CACNA1G (0.36) | GPR119HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL7433171 | 0.73 | MMP13 (0.48) | GPR119HTR2CSLC6A4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |