Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25905691 | 0.77 | CYP3A4 (0.36) | RAB9ANAMPTMAPTATMTRPA1 | |
| SCHEMBL16692646 | 0.76 | NAMPT (0.46) | RAB9ANAMPTL3MBTL1MAPTCYP17A1 | |
| SCHEMBL6947166 | 0.76 | CTSK (0.47) | NAMPTALDH1A1L3MBTL1KMT2ACTSK | |
| SCHEMBL31407188 | 0.75 | RIPK1 (0.37) | RAB9ANAMPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL23674773 | 0.75 | CYP17A1 (0.48) | RAB9ANAMPTCYP17A1 | |
| SCHEMBL31407248 | 0.74 | SLC6A2 (0.38) | TRPV1ALDH1A1L3MBTL1CYP3A4SMN1; SMN2 | |
| SCHEMBL31568942 | 0.73 | IDO1 (0.46) | NAMPTALDH1A1KMT2ATSHRCYP3A4 | |
| SCHEMBL19753998 | 0.73 | ALOX5 (0.46) | RAB9AALDH1A1L3MBTL1KMT2AMAPT | |
| SCHEMBL3889017 | 0.72 | PIM1 (0.37) | RAB9ANAMPTL3MBTL1KMT2AMAPT | |
| SCHEMBL12018154 | 0.72 | CYP17A1 (0.48) | RAB9ANAMPTCYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |