Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | JAK1 | P23458 | 4/20 | 0.33 |
| ▸ | JAK3 | P52333 | 4/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408537 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2JAK2JAK3LRRK2MAPK1 | |
| SCHEMBL31408430 | 0.87 | MAPK1 (0.37) | SMN1; SMN2MAPK1PTGES | |
| SCHEMBL31408237 | 0.85 | LRRK2 (0.35) | SMN1; SMN2JAK2JAK3LRRK2MAPK1 | |
| SCHEMBL31408327 | 0.85 | LRRK2 (0.35) | SMN1; SMN2JAK2JAK3LRRK2MAPK1 | |
| SCHEMBL31408429 | 0.85 | LRRK2 (0.35) | SMN1; SMN2JAK2JAK3LRRK2MAPK1 | |
| SCHEMBL31408514 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPK1PDCD1CD274PTGES | |
| SCHEMBL31408279 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2LRRK2MAPK1PTGES | |
| SCHEMBL31408356 | 0.84 | POLB (0.39) | SMN1; SMN2LRRK2MAPK1 | |
| SCHEMBL31408404 | 0.84 | LRRK2 (0.36) | SMN1; SMN2LRRK2MAPK1PDCD1CD274 | |
| SCHEMBL31408407 | 0.83 | MAP4K1 (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |