Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 4/20 | 0.44 |
| ▸ | METTL14 | Q9HCE5 | 4/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 10/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | FES | P07332 | 2/20 | 0.43 |
| ▸ | ROS1 | P08922 | 2/20 | 0.43 |
| ▸ | FER | P16591 | 2/20 | 0.43 |
| ▸ | FLT4 | P35916 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.43 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408351 | 0.83 | SMN1; SMN2 (0.40) | AURKBSMN1; SMN2 | |
| SCHEMBL31408571 | 0.82 | SMN1; SMN2 (0.41) | CDK8CCNCSMN1; SMN2 | |
| SCHEMBL31408611 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL31408594 | 0.82 | SMN1; SMN2 (0.38) | AURKBSMN1; SMN2 | |
| SCHEMBL31408586 | 0.82 | SMN1; SMN2 (0.40) | AURKBSMN1; SMN2 | |
| SCHEMBL31408238 | 0.82 | SMN1; SMN2 (0.40) | AURKBSMN1; SMN2 | |
| SCHEMBL31408448 | 0.81 | RAB9A (0.38) | SMN1; SMN2 | |
| SCHEMBL31408473 | 0.81 | SMN1; SMN2 (0.37) | ROCK1ROCK2SMN1; SMN2 | |
| SCHEMBL31408250 | 0.81 | PRKAG1 (0.48) | AURKBSYKSMN1; SMN2 | |
| SCHEMBL31408452 | 0.80 | SMN1; SMN2 (0.44) | CDK8ROCK2CCNCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |