Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 7/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408594 | 0.91 | SMN1; SMN2 (0.38) | RAB9ANPC1SMN1; SMN2BDKRB1MTNR1A | |
| SCHEMBL31408442 | 0.88 | SMN1; SMN2 (0.36) | RAB9ANPC1SMN1; SMN2BDKRB1MTNR1A | |
| SCHEMBL31408473 | 0.88 | SMN1; SMN2 (0.37) | RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL31408333 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2MTNR1AMTNR1BMAPT | |
| SCHEMBL31408351 | 0.86 | SMN1; SMN2 (0.40) | RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL31408611 | 0.85 | SMN1; SMN2 (0.41) | RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL31408461 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2MTNR1AMTNR1BMAPTKDM4E | |
| SCHEMBL31408362 | 0.81 | METTL3 (0.44) | SMN1; SMN2 | |
| SCHEMBL31408238 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2MTNR1AMTNR1BMAPTKDM4E | |
| SCHEMBL31408267 | 0.80 | SMN1; SMN2 (0.40) | RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |