Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027289 | 0.88 | SMN1; SMN2 (0.45) | SCN1ASCN2ASCN3AALDH1A1SMN1; SMN2 | |
| SCHEMBL3135698 | 0.85 | SOAT1 (0.44) | SCN1ASCN2ASCN3AALDH1A1TP53 | |
| SCHEMBL18498551 | 0.81 | CRHR1 (0.44) | SCN1ASCN2ASCN3ASOAT1PTPN1 | |
| SCHEMBL28724605 | 0.79 | KCNH2 (0.46) | ALDH1A1TP53SOAT1 | |
| SCHEMBL3302286 | 0.78 | KCNH2 (0.45) | SOAT1 | |
| SCHEMBL11234182 | 0.77 | PPARG (0.55) | ALDH1A1TP53LTA4HPPARGSMN1; SMN2 | |
| SCHEMBL12983559 | 0.76 | CRHR1 (0.46) | SCN1ASCN2ASCN3ASOAT1ESR1 | |
| SCHEMBL18055614 | 0.74 | TDP1 (0.53) | ALDH1A1LTA4HPPARGSMN1; SMN2KDM4E | |
| SCHEMBL9188630 | 0.73 | PPARG (0.54) | ALDH1A1TP53LTA4HPPARGSMN1; SMN2 | |
| SCHEMBL11325151 | 0.72 | ALOX5 (0.48) | SCN1ASCN2ASCN3AALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216772-A1 | Novel Phenantridine Analogues and Uses Thereof | 4SC AG (DE) | 2010-08-26 | — | — | US | disclosed |
| EP-1740548-A1 | NOVEL PHENANTRIDINE ANALOGUES AND THEIR USES AS INHIBITORS OF HYPERPROLIFERATION OF T CELLS AND/OR KERATINOCYTES | 4SC AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105752-A1 | NOVEL PHENANTRIDINE ANALOGUES AND THEIR USES AS INHIBITORS OF HYPERPROLIFERATION OF T CELLS AND/OR KERATINOCYTES | 4SC AG (DE) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216772-A1 | Novel Phenantridine Analogues and Uses Thereof | P2RX4, P2RX5, CLIC4 | SCN1A 652/4885SCN2A 617/4885SCN3A 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.