Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408594 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2MTNR1AMTNR1BMAPTSCN9A | |
| SCHEMBL31408448 | 0.87 | RAB9A (0.38) | SMN1; SMN2MTNR1AMTNR1BMAPT | |
| SCHEMBL31408442 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2MTNR1AMTNR1BMAPTSCN9A | |
| SCHEMBL31408461 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2MTNR1AMTNR1BMAPTMAPK1 | |
| SCHEMBL31408354 | 0.83 | PRKAG1 (0.48) | SMN1; SMN2MTNR1AMTNR1BPIK3CG | |
| SCHEMBL31408473 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2MTNR1AMTNR1BMAPTF2 | |
| SCHEMBL31408611 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2MTNR1AMTNR1BMAPT | |
| SCHEMBL31408283 | 0.82 | MTNR1A (0.47) | SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL31408351 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2MTNR1AMTNR1BMAPT | |
| SCHEMBL31408618 | 0.81 | MTNR1A (0.43) | SMN1; SMN2MTNR1AMTNR1BPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |