Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408351 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2MTNR1AMTNR1BAURKAAURKB | |
| SCHEMBL31408354 | 0.88 | PRKAG1 (0.48) | SMN1; SMN2MTNR1AMTNR1BPTGESAURKA | |
| SCHEMBL31408333 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2MTNR1AMTNR1BMAPTMAPK1 | |
| SCHEMBL31408629 | 0.83 | PTGES (0.42) | SMN1; SMN2MTNR1AMTNR1BPTGESDYRK1A | |
| SCHEMBL31408618 | 0.83 | MTNR1A (0.43) | SMN1; SMN2MTNR1AMTNR1BPTGESAURKA | |
| SCHEMBL31408595 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2MTNR1AMTNR1BAURKAAURKB | |
| SCHEMBL31408611 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2MTNR1AMTNR1BPRKAG1PRKAA1 | |
| SCHEMBL31408619 | 0.83 | MTNR1A (0.44) | SMN1; SMN2MTNR1AMTNR1BPTGESAURKA | |
| SCHEMBL31408586 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2MTNR1AMTNR1BABL1AURKA | |
| SCHEMBL31408594 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2MTNR1AMTNR1BAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |