Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 3/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408404 | 0.88 | LRRK2 (0.36) | SMN1; SMN2PTGESEPHX2MAPK1 | |
| SCHEMBL31408312 | 0.86 | PTGES (0.37) | SMN1; SMN2PTGES | |
| SCHEMBL31408356 | 0.85 | POLB (0.39) | SMN1; SMN2MAPK1 | |
| SCHEMBL31408430 | 0.84 | MAPK1 (0.37) | SMN1; SMN2PTGESEPHX2MAPK1 | |
| SCHEMBL31408419 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2PTGES | |
| SCHEMBL31408232 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2PTGES | |
| SCHEMBL31408414 | 0.83 | PTGES (0.35) | SMN1; SMN2PTGES | |
| SCHEMBL31408509 | 0.83 | SMN1; SMN2 (0.34) | SMN1; SMN2PTGESEPHX2MAPK1 | |
| SCHEMBL31408447 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2PTGES | |
| SCHEMBL31408551 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2PTGESSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |