SCHEMBL3140867

SCHEMBL3140867

COc1cccc(S(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 1/20 0.44
RORC P51449 1/20 0.44
NR1H2 P55055 1/20 0.44
ABCC9 O60706 1/20 0.42
ABCC8 Q09428 1/20 0.42
KCNJ11 Q14654 1/20 0.42
KCNJ8 Q15842 1/20 0.42
PGR P06401 4/20 0.41
NFE2L2 Q16236 4/20 0.40
KEAP1 Q14145 3/20 0.40
TAS2R14 Q9NYV8 1/20 0.39
HSD11B1 P28845 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
CTSG P08311 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3139661 1.00 RORA (0.44) RORARORCNR1H2ABCC9ABCC8
SCHEMBL3144127 0.99 RORA (0.45) RORARORCNR1H2ABCC9ABCC8
SCHEMBL2914111 0.89 HSD11B1 (0.43) PGRNFE2L2KEAP1HSD11B1CA1
SCHEMBL3144470 0.89 HSD11B1 (0.43) PGRNFE2L2KEAP1HSD11B1CA1
SCHEMBL3132698 0.89 HSD11B1 (0.43) PGRNFE2L2KEAP1HSD11B1CA1
SCHEMBL3132264 0.89 HSD11B1 (0.43) PGRNFE2L2KEAP1HSD11B1CA1
SCHEMBL3126981 0.87 HSD11B1 (0.44) PGRNFE2L2KEAP1HSD11B1CA1
SCHEMBL270993 0.87 HSD11B1 (0.44) PGRNFE2L2KEAP1HSD11B1CA1
SCHEMBL3135952 0.86 RORA (0.47) RORARORCNR1H2ABCC9ABCC8
SCHEMBL60138 0.85 CA2 (0.44) NR1H2HSD11B1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed