SCHEMBL3144470

SCHEMBL3144470

COc1ccc(S(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.43
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.39
ALDH1A1 P00352 3/20 0.38
PGR P06401 2/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SQSTM1 Q13501 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132698 1.00 HSD11B1 (0.43) HSD11B1CA1CA2KMT2AGAA
SCHEMBL3132264 1.00 HSD11B1 (0.43) HSD11B1CA1CA2KMT2AGAA
SCHEMBL2914111 1.00 HSD11B1 (0.43) HSD11B1CA1CA2KMT2AGAA
SCHEMBL3126981 0.99 HSD11B1 (0.44) HSD11B1CA1CA2KMT2AGAA
SCHEMBL270993 0.99 HSD11B1 (0.44) HSD11B1CA1CA2KMT2AGAA
SCHEMBL1593151 0.95 HSD11B1 (0.45) HSD11B1KMT2AGAAPKMALDH1A1
SCHEMBL503836 0.95 HSD11B1 (0.47) HSD11B1CA1CA2KMT2AGAA
SCHEMBL454991 0.93 HSD11B1 (0.48) HSD11B1CA1CA2KMT2AGAA
SCHEMBL4535203 0.89 CA2 (0.44) HSD11B1CA1CA2
SCHEMBL60138 0.89 CA2 (0.44) HSD11B1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed