SCHEMBL31409443

SCHEMBL31409443

[2H]C([2H])([2H])O[C@H](C)COc1ccc(C=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 1/20 0.47
ALDH1A1 P00352 7/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
LMNA P02545 3/20 0.44
HPGD P15428 3/20 0.44
MAPT P10636 3/20 0.44
CYP2A6 P11509 1/20 0.43
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TYR P14679 1/20 0.39
KDM4E B2RXH2 4/20 0.39
NPC1 O15118 2/20 0.39
MTOR P42345 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5367181 0.81 ALDH1A3 (0.61) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL31371156 0.80 KDM4E (0.46) ALDH1A3ALDH1A1TYRKDM4EL3MBTL1
SCHEMBL970318 0.79 ALDH1A3 (0.57) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL9745966 0.76 ALDH1A1 (0.53) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL3595449 0.76 LMNA (0.58) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL1931817 0.76 LMNA (0.58) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL27995838 0.75 ALDH1A1 (0.46) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL27995836 0.75 ALDH1A1 (0.46) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL17070011 0.75 ALDH1A1 (0.50) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL9470287 0.75 ALDH1A3 (0.52) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038783-A1 ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS OR CHRONIC HEART FAILURE LUCY THERAPEUTICS, INC. (US) 2025-02-20 WO disclosed