SCHEMBL5367181

SCHEMBL5367181

CC(COc1ccc(C=O)cc1)Oc1ccc(C=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 1/20 0.61
ALDH1A1 P00352 6/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
LMNA P02545 3/20 0.47
HPGD P15428 3/20 0.47
MAPT P10636 2/20 0.47
DRD1 P21728 1/20 0.47
CYP2A6 P11509 1/20 0.47
TYR P14679 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
KDM4E B2RXH2 3/20 0.41
NPC1 O15118 1/20 0.41
MTOR P42345 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL970318 0.83 ALDH1A3 (0.57) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL16353393 0.81 ALDH1A3 (0.66) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL31409443 0.81 ALDH1A3 (0.47) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL1931653 0.80 ALDH1A3 (0.63) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL1931817 0.80 LMNA (0.58) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL241310 0.80 ALDH1A3 (0.63) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL3595449 0.80 LMNA (0.58) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL8372769 0.79 ALDH1A3 (0.53) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL8372459 0.79 ALDH1A3 (0.53) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL27995836 0.79 ALDH1A1 (0.46) ALDH1A3ALDH1A1SMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169446-B2 Oxetane compound, actinic ray curable composition, ink composition for ink jet recording, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-30 US disclosed
EP-1486526-B1 Oxetane compound, actinic ray curable composition, ink composition for ink jet recording, and image formation method KONICA MINOLTA MED & GRAPHIC (JP) 2006-08-16 EP disclosed
US-20040252171-A1 Oxetane compound, actinic ray curable composition, ink composition for ink jet recording, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2004-12-16 US disclosed
EP-1486526-A1 Oxetane compound, actinic ray curable composition, ink composition for ink jet recording, and image formation method Konica Minolta Medical & Graphic, Inc. (JP) 2004-12-15 EP disclosed
EP-0802199-B1 Covalently bound dimers of glycopeptide antibiotics LILLY CO ELI (US) 1999-12-08 EP disclosed
EP-0802199-A2 Covalently bound dimers of glycopetide antibiotics ELI LILLY AND COMPANY (US) 1997-10-22 EP disclosed