Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409687 | 0.78 | GRM2 (0.30) | — | |
| SCHEMBL31409643 | 0.77 | CYP1A2 (0.34) | CYP1A2CYP2C9BLMGRM5MAPK1 | |
| SCHEMBL31409595 | 0.65 | L3MBTL1 (0.44) | CYP1A2CYP2C9BLM | |
| SCHEMBL31409610 | 0.63 | CYP1A2 (0.34) | CYP1A2CYP2C9BLMMAPK1 | |
| SCHEMBL31409646 | 0.62 | AURKA (0.34) | CYP1A2CYP2C9BLMMAPK1 | |
| SCHEMBL31409570 | 0.61 | P2RX3 (0.34) | — | |
| SCHEMBL16396910 | 0.60 | CYP1A2 (0.42) | CYP1A2CYP2C9BLMGRM5 | |
| SCHEMBL20406377 | 0.59 | BLM (0.48) | CYP1A2CYP2C9BLMGRM5 | |
| SCHEMBL30591957 | 0.59 | GRM5 (0.42) | CYP1A2CYP2C9BLMGRM5 | |
| SCHEMBL26108227 | 0.59 | GRM5 (0.42) | CYP1A2CYP2C9BLMGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |