Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409687 | 0.77 | GRM2 (0.30) | — | |
| SCHEMBL31409607 | 0.77 | CYP1A2 (0.34) | CYP1A2CYP2C9GRM5MAPK1BLM | |
| SCHEMBL31409676 | 0.76 | JAK3 (0.35) | DYRK1ANFATC1PIM1DYRK2DYRK1B | |
| SCHEMBL31409705 | 0.73 | DYRK1A (0.36) | DYRK1APIM1MAPTSCN9A | |
| SCHEMBL31409595 | 0.70 | L3MBTL1 (0.44) | CYP1A2CYP2C9KDM4ECYP2C19ATM | |
| SCHEMBL3192003 | 0.66 | LTA4H (0.41) | CYP1A2CYP2C9DYRK1APIM1CYP2C19 | |
| SCHEMBL16396910 | 0.66 | CYP1A2 (0.42) | CYP1A2CYP2C9GRM5KDM4ECYP2C19 | |
| SCHEMBL14115579 | 0.64 | LRRK2 (0.50) | DYRK1APIM1 | |
| SCHEMBL16396103 | 0.63 | CYP1A2 (0.44) | CYP1A2CYP2C9GRM5KDM4ECYP2C19 | |
| SCHEMBL30591776 | 0.63 | GRM5 (0.41) | CYP1A2CYP2C9GRM5MAPTSCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |