SCHEMBL31409757

SCHEMBL31409757

Fc1c(F)c(F)c2c(-c3ccc(C(F)(F)F)cc3)c3c(F)c(F)c(F)c(F)c3c(-c3ccc(C(F)(F)F)cc3)c2c1F

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 10/20 0.48
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
MAOB P27338 1/20 0.38
HEXA P06865 1/20 0.38
HEXB P07686 1/20 0.38
BACE1 P56817 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
TRPV6 Q9H1D0 1/20 0.37
MGLL Q99685 1/20 0.37
NISCH Q9Y2I1 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21001760 1.00 KIF11 (0.48) KIF11ALDH1A1TSHRMAOBHEXA
SCHEMBL4138734 0.86 KIF11 (0.52) KIF11ALDH1A1TSHRMAOBHEXA
SCHEMBL29947885 0.77 MKNK1 (0.47) KIF11MAOBNISCH
SCHEMBL28248236 0.76 KIF11 (0.46) KIF11ALDH1A1TSHRMAOB
SCHEMBL12402901 0.76 KIF11 (0.58) KIF11ALDH1A1TSHRBACE1TRPV6
SCHEMBL197238 0.74 KIF11 (0.78) KIF11ALDH1A1TSHRMAOBCES2
SCHEMBL29914837 0.74 KIF11 (0.78) KIF11ALDH1A1TSHRMAOBCES2
SCHEMBL13410633 0.74 KIF11 (0.78) KIF11ALDH1A1TSHRMAOBCES2
SCHEMBL20769886 0.74 KIF11 (0.48) KIF11HEXAHEXBNISCH
SCHEMBL17567432 0.71 ALDH1A1 (0.45) KIF11ALDH1A1MGLLCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836862-A Organic thin film, organic electroluminescent element, display device, lighting device, organic thin film solar cell, and organic thin film transistor 日本放送协会 2025-04-15 CN disclosed