SCHEMBL31410641

SCHEMBL31410641

CCOC(=O)C(F)(F)C(O)c1ccc(Cl)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.39
ABCB11 O95342 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
HTR2A P28223 1/20 0.39
PMP22 Q01453 1/20 0.39
FBP1 P09467 5/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
LMNA P02545 3/20 0.37
PPARG P37231 1/20 0.37
FFAR1 O14842 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30676269 0.89 SLC6A3 (0.45) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL29570448 0.89 SLC6A3 (0.45) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL25220032 0.82 ABCB11 (0.54) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL29570205 0.80 MAPT (0.46) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL9316536 0.80 MAPT (0.46) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL22397206 0.79 SLC6A2 (0.42) PPARATSHRLMNAPPARGFFAR1
SCHEMBL31410600 0.77 APP (0.37) PPARAPPARGFFAR1GPR139
SCHEMBL16595185 0.77 GABBR2 (0.52) CYP1A2TSHRNPSR1MEN1KMT2A
SCHEMBL1932881 0.76 SLC6A2 (0.39) MAPK1LMNAFFAR1SLC6A2SLC6A4
SCHEMBL29571136 0.76 PPARA (0.42) PPARAABCB11CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076017-A1 CARBAMATES FOR USE AS SARM1 INHIBITORS GENENTECH, INC. (US) 2025-04-10 WO disclosed