Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1949394 | 1.00 | THRB (0.36) | THRBALDH1A1LMNA | |
| SCHEMBL14587569 | 0.89 | DUT (0.34) | THRB | |
| SCHEMBL15508218 | 0.89 | DUT (0.34) | THRB | |
| SCHEMBL15520841 | 0.89 | DUT (0.34) | THRB | |
| SCHEMBL14513909 | 0.87 | USP2 (0.33) | THRB | |
| SCHEMBL8329760 | 0.87 | USP2 (0.33) | THRB | |
| SCHEMBL23042973 | 0.84 | — | — | |
| SCHEMBL14365667 | 0.84 | TSHR (0.30) | — | |
| SCHEMBL14119498 | 0.84 | — | — | |
| SCHEMBL27078172 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304604-A1 | ORGANOSILANES FOR THE TREATMENT OF INFECTIONS | TOPIKOS SCIENTIFIC, INC. (US) | 2025-10-02 | — | — | US | disclosed |
| US-12180239-B2 | Organosilanes for the treatment of infections | TOPIKOS SCIENTIFIC, INC. (US) | 2024-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12180239-B2 | Organosilanes for the treatment of infections | ASNS, ACMSD, ARG1 | THRB 4843/4885ALDH1A1 1902/4885LMNA 4264/4885 |
| US-20250304604-A1 | ORGANOSILANES FOR THE TREATMENT OF INFECTIONS | ASNS, ACMSD, ARG1 | THRB 4843/4885ALDH1A1 1902/4885LMNA 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.