SCHEMBL31411268

SCHEMBL31411268

COc1cc2c(CCO)nn(C3CCCCO3)c2cc1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
ATR Q13535 2/20 0.34
TEAD1 P28347 1/20 0.33
TEAD4 Q15561 1/20 0.33
TEAD2 Q15562 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
ACVR1 Q04771 1/20 0.32
SCN9A Q15858 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
EGFR P00533 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411414 0.88 HTR1A (0.38) CYP4F2CYP4A11ATRTEAD1TEAD4
SCHEMBL31411287 0.87 ATR (0.35) CYP4F2CYP4A11ATRALDH1A1
SCHEMBL31651558 0.87 ATR (0.35) CYP4F2CYP4A11ATRALDH1A1LMNA
SCHEMBL31411321 0.86 ATR (0.36) CYP4F2CYP4A11ATRALDH1A1HSD17B10
SCHEMBL31411310 0.85 LMNA (0.35) CYP4F2CYP4A11ATRTEAD1TEAD4
SCHEMBL31411440 0.85 ATR (0.32) CYP4F2CYP4A11ATRLMNASCN9A
SCHEMBL31411429 0.85 ATR (0.32) CYP4F2CYP4A11ATRLMNASCN9A
SCHEMBL31411467 0.85 HRH3 (0.34) CYP4F2CYP4A11ATR
SCHEMBL31411345 0.82 ATR (0.36) CYP4F2CYP4A11ATRALDH1A1HSD17B10
SCHEMBL31411354 0.82 ATR (0.36) CYP4F2CYP4A11ATRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB CYP4F2 614/4885CYP4A11 1465/4885ATR 2191/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB CYP4F2 614/4885CYP4A11 1465/4885ATR 2191/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB CYP4F2 614/4885CYP4A11 1465/4885ATR 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.