SCHEMBL31411429

SCHEMBL31411429

COc1cc2c(CCN3CC4CC4C3)nn(C3CCCCO3)c2cc1F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ATR Q13535 1/20 0.32
LMNA P02545 1/20 0.31
ADRA1B P35368 1/20 0.31
SCN9A Q15858 1/20 0.31
FPR2 P25090 1/20 0.31
PROKR1 Q8TCW9 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
PDE1B Q01064 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411440 0.92 ATR (0.32) ATRLMNASCN9ACYP4F2CYP4A11
SCHEMBL31411287 0.90 ATR (0.35) ATRCYP4F2CYP4A11
SCHEMBL31651558 0.90 ATR (0.35) ATRLMNACYP4F2CYP4A11
SCHEMBL31411421 0.85 ATR (0.32) ATR
SCHEMBL31411268 0.85 CYP4F2 (0.35) ATRLMNASCN9ACYP4F2CYP4A11
SCHEMBL31411467 0.84 HRH3 (0.34) ATRCYP4F2CYP4A11
SCHEMBL31411414 0.83 HTR1A (0.38) ATRLMNASCN9ACYP4F2CYP4A11
SCHEMBL31411321 0.81 ATR (0.36) ATRLMNASCN9ACYP4F2CYP4A11
SCHEMBL31411310 0.81 LMNA (0.35) ATRLMNAADRA1BCYP4F2CYP4A11
SCHEMBL31411345 0.77 ATR (0.36) ATRLMNASCN9ACYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB ATR 2191/4885LMNA 2980/4885ADRA1B 2108/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB ATR 2191/4885LMNA 2980/4885ADRA1B 2108/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB ATR 2191/4885LMNA 2980/4885ADRA1B 2108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.