SCHEMBL31411340

SCHEMBL31411340

COc1ccc(F)c2[nH]nc(CCN(C)C(C)C)c12

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ HTR1A P08908 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL31411333 0.91 SLC6A2 (0.35) KDM4EALDH1A1
SCHEMBL31411305 0.87 HTR1A (0.43) HTR1AKDM4EALDH1A1HTR2A
SCHEMBL31411332 0.84 ALDH1A1 (0.36) HTR1AKDM4EALDH1A1HTR2A
SCHEMBL31411312 0.81 HTR1A (0.45) HTR1AHTR2A
Fumaric Acid SCHEMBL31411436 0.78 NPSR1 (0.37) HTR1AKDM4EALDH1A1HTR2A
SCHEMBL31411330 0.78 HTR1A (0.30) HTR1AHTR2A
SCHEMBL25748542 0.77 HTR1A (0.51) HTR1AKDM4EALDH1A1HTR2A
SCHEMBL30483731 0.77 HTR1A (0.51) HTR1AKDM4EALDH1A1HTR2A
SCHEMBL31411401 0.76 MAPK1 (0.32) HTR1A
SCHEMBL31411411 0.74 HTR2A (0.37) ALDH1A1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885KDM4E 3243/4885ALDH1A1 981/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885KDM4E 3243/4885ALDH1A1 981/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB HTR1A 185/4885KDM4E 3243/4885ALDH1A1 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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