SCHEMBL31411411

SCHEMBL31411411

COc1cc(F)c2[nH]nc(CCN(C)C(C)C)c2c1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 2/20 0.37
▸ HTR2C P28335 2/20 0.37
▸ HTR2B P41595 2/20 0.37
▸ TAAR1 Q96RJ0 1/20 0.34
▸ ALDH1A1 P00352 3/20 0.33
▸ GRK6 P43250 1/20 0.31
▸ CFTR P13569 1/20 0.30
▸ HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411392 0.85 GPR84 (0.33) —
SCHEMBL31411284 0.85 HTR2A (0.41) HTR2AHTR2CHTR2BTAAR1ALDH1A1
Formic Acid SCHEMBL31411275 0.82 HTR2A (0.43) HTR2AHTR2CHTR2BTAAR1GRK6
SCHEMBL25249523 0.79 HTR2A (0.46) HTR2AHTR2CHTR2BALDH1A1HTR6
Hydrochloric Acid SCHEMBL30565940 0.78 HTR2A (0.45) HTR2AHTR2CHTR2BALDH1A1HTR6
SCHEMBL30483738 0.78 MTNR1A (0.45) HTR2AHTR2CHTR2BHTR6
SCHEMBL25748616 0.78 MTNR1A (0.45) HTR2AHTR2CHTR2BHTR6
SCHEMBL31411350 0.77 HTR1A (0.45) HTR2B
SCHEMBL31411434 0.74 HTR2A (0.44) HTR2AALDH1A1CFTR
SCHEMBL31411389 0.74 HTR2A (0.43) HTR2AALDH1A1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB HTR2A 94/4885HTR2C 23/4885HTR2B 114/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB HTR2A 94/4885HTR2C 23/4885HTR2B 114/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB HTR2A 94/4885HTR2C 23/4885HTR2B 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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