SCHEMBL31411356

SCHEMBL31411356

COc1cc2c(CCN(C)C(C)C)nn(COCC[Si](C)(C)C)c2cc1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.32
HTR1A P08908 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411339 0.85 ACVR1 (0.32) DGAT1HTR1A
SCHEMBL31411397 0.84 DGAT1 (0.35) DGAT1
SCHEMBL31411374 0.83 DGAT1 (0.37) DGAT1
SCHEMBL31411408 0.83 DGAT1 (0.32) DGAT1
SCHEMBL25248211 0.82 HTR6 (0.38) DGAT1HTR1A
SCHEMBL31411279 0.82 EGFR (0.33) DGAT1
SCHEMBL31411377 0.81 DGAT1 (0.34) DGAT1
SCHEMBL31411388 0.81 DGAT1 (0.34) DGAT1
SCHEMBL31411329 0.81 HTR1A (0.31) DGAT1HTR1A
SCHEMBL31411412 0.79 DGAT1 (0.35) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB DGAT1 1102/4885HTR1A 185/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB DGAT1 1102/4885HTR1A 185/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB DGAT1 1102/4885HTR1A 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.