SCHEMBL31411396

SCHEMBL31411396

C[Si](C)(C)CCOCn1nc(CCN)c2c(F)cccc21

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
DGAT1 O75907 3/20 0.35
ALOX5AP P20292 4/20 0.34
FEN1 P39748 4/20 0.34
F2RL1 P55085 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411270 0.89 NPC1 (0.35) NPC1DGAT1ALOX5APFEN1F2RL1
SCHEMBL31411293 0.87 HTR2A (0.35) NPC1DGAT1ALOX5APFEN1F2RL1
SCHEMBL31411410 0.85 NPC1 (0.34) NPC1DGAT1ALOX5APFEN1F2RL1
SCHEMBL31460042 0.81 DGAT1 (0.36) NPC1DGAT1ALOX5APFEN1F2RL1
SCHEMBL31411458 0.79 F2RL1 (0.35) NPC1DGAT1ALOX5APFEN1F2RL1
SCHEMBL31411385 0.79 F2RL1 (0.35) NPC1DGAT1ALOX5APFEN1F2RL1
SCHEMBL31411357 0.78 RORC (0.40)
SCHEMBL25170244 0.77 ALOX5AP (0.35) NPC1DGAT1ALOX5APFEN1F2RL1
SCHEMBL31411302 0.73 DGAT1 (0.36) NPC1DGAT1F2RL1
SCHEMBL31411402 0.73 F2RL1 (0.35) DGAT1F2RL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB NPC1 539/4885DGAT1 1102/4885ALOX5AP 1683/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB NPC1 539/4885DGAT1 1102/4885ALOX5AP 1683/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB NPC1 539/4885DGAT1 1102/4885ALOX5AP 1683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.