SCHEMBL31411407

SCHEMBL31411407

COc1c(F)ccc2c1c(CCN(C)C(C)C)nn2COCC[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.33
DGAT1 O75907 2/20 0.32
CCR4 P51679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411418 0.90 DGAT1 (0.34) F2RL1DGAT1
SCHEMBL31411325 0.87 F2RL1 (0.33) F2RL1DGAT1
SCHEMBL31411329 0.86 HTR1A (0.31) DGAT1
SCHEMBL31411276 0.85 DGAT1 (0.31) F2RL1DGAT1
SCHEMBL31411402 0.84 F2RL1 (0.35) F2RL1DGAT1CCR4
SCHEMBL31411370 0.83 F2RL1 (0.33) F2RL1DGAT1
SCHEMBL31411336 0.82 CCR4 (0.35) F2RL1DGAT1CCR4
SCHEMBL31411408 0.81 DGAT1 (0.32) DGAT1
SCHEMBL31411374 0.79 DGAT1 (0.37) DGAT1
SCHEMBL31411356 0.79 DGAT1 (0.32) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB F2RL1 4296/4885DGAT1 1102/4885CCR4 4209/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB F2RL1 4296/4885DGAT1 1102/4885CCR4 4209/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB F2RL1 4296/4885DGAT1 1102/4885CCR4 4209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.