SCHEMBL31411469

SCHEMBL31411469

COc1cc2c(CCN3CCC4CC43)n[nH]c2cc1F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MTNR1A P48039 1/20 0.34
▸ MTNR1B P49286 1/20 0.34
▸ HTR1A P08908 5/20 0.34
▸ TLR8 Q9NR97 3/20 0.34
▸ DRD2 P14416 2/20 0.34
▸ TLR7 Q9NYK1 2/20 0.34
▸ LRRK2 Q5S007 10/20 0.33
▸ FPR2 P25090 1/20 0.32
▸ PROKR1 Q8TCW9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL31651565 0.92 MTNR1A (0.35) MTNR1AMTNR1BTLR8TLR7LRRK2
SCHEMBL31411298 0.88 HRH3 (0.38) MTNR1AMTNR1BHTR1ATLR8TLR7
SCHEMBL31411426 0.81 HTR1A (0.34) HTR1ADRD2
SCHEMBL31411424 0.81 HTR1A (0.34) HTR1ADRD2
Fumaric Acid SCHEMBL31411409 0.81 MTNR1A (0.37) MTNR1AMTNR1BTLR8LRRK2
SCHEMBL31411491 0.81 HTR1A (0.36) MTNR1AMTNR1BHTR1ALRRK2FPR2
SCHEMBL31411295 0.80 HTR1A (0.34) HTR1ADRD2FPR2PROKR1
SCHEMBL31411485 0.79 LRRK2 (0.37) MTNR1AMTNR1BHTR1ALRRK2
SCHEMBL31411448 0.79 HTR1A (0.40) HTR1ADRD2LRRK2
SCHEMBL31651554 0.79 HTR1A (0.42) HTR1ADRD2LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB MTNR1A 888/4885MTNR1B 461/4885HTR1A 185/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB MTNR1A 888/4885MTNR1B 461/4885HTR1A 185/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB MTNR1A 888/4885MTNR1B 461/4885HTR1A 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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