Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411650 | 0.89 | GSK3A (0.54) | SMN1; SMN2KMT2AGSK3BGSK3ACYP2C19 | |
| SCHEMBL6991944 | 0.82 | KCNN4 (0.48) | SMN1; SMN2KMT2AKDM4EGSK3BGSK3A | |
| SCHEMBL29978554 | 0.80 | ALDH1A1 (0.64) | SMN1; SMN2GSK3BCYP2C19NPSR1MAPT | |
| SCHEMBL21972975 | 0.80 | ALDH1A1 (0.64) | SMN1; SMN2GSK3BCYP2C19NPSR1MAPT | |
| SCHEMBL31411536 | 0.80 | GSK3B (0.56) | SMN1; SMN2KMT2AGSK3BGSK3ACYP2C19 | |
| SCHEMBL31411751 | 0.79 | GSK3A (0.45) | SMN1; SMN2KMT2AGSK3BGSK3ACYP2C19 | |
| SCHEMBL31411697 | 0.75 | SIRT2 (0.39) | SMN1; SMN2KMT2AKDM4EGSK3BGSK3A | |
| SCHEMBL6989440 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AKDM4EGSK3BGSK3A | |
| SCHEMBL6991096 | 0.71 | GSK3A (0.46) | SMN1; SMN2KMT2AKDM4EGSK3BGSK3A | |
| SCHEMBL6993171 | 0.70 | GSK3A (0.54) | SMN1; SMN2KMT2AGSK3BGSK3ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |