Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411871 | 0.89 | ALDH1A1 (0.40) | PTGDR2POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6991944 | 0.85 | KCNN4 (0.48) | KCNN4POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL31411665 | 0.82 | KCNN4 (0.42) | KCNN4HTR7POLBSMN1; SMN2MAPT | |
| SCHEMBL31411598 | 0.81 | KCNN4 (0.41) | KCNN4POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL31411715 | 0.81 | ALDH1A1 (0.52) | POLBSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL31411767 | 0.80 | ALDH1A1 (0.52) | KCNN4POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6996076 | 0.80 | ALDH1A1 (0.41) | KCNN4POLBSMN1; SMN2MAPTHPGD | |
| SCHEMBL31411740 | 0.79 | POLB (0.58) | POLBSMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL31411693 | 0.79 | POLB (0.50) | HTR7POLBSMN1; SMN2MAPTHPGD | |
| SCHEMBL6989440 | 0.77 | ALDH1A1 (0.50) | KCNN4POLBSMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |