Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411849 | 0.89 | ALDH1A1 (0.41) | SMN1; SMN2POLBMAPTNPC1GSK3B | |
| SCHEMBL6991944 | 0.86 | KCNN4 (0.48) | KCNN4SMN1; SMN2POLBMAPTGSK3B | |
| SCHEMBL31411679 | 0.82 | KCNN4 (0.42) | KCNN4SMN1; SMN2POLBMAPTHPGD | |
| SCHEMBL31411767 | 0.81 | ALDH1A1 (0.52) | KCNN4SMN1; SMN2POLBMAPTNPC1 | |
| SCHEMBL6996076 | 0.81 | ALDH1A1 (0.41) | KCNN4SMN1; SMN2POLBMAPTHPGD | |
| SCHEMBL31411575 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBMAPTHPGDHTR7 | |
| SCHEMBL31411598 | 0.78 | KCNN4 (0.41) | KCNN4SMN1; SMN2POLBMAPTNPC1 | |
| SCHEMBL31411715 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2POLBMAPTALDH1A1KMT2A | |
| SCHEMBL6989440 | 0.77 | ALDH1A1 (0.50) | KCNN4SMN1; SMN2POLBMAPTGSK3B | |
| SCHEMBL31411562 | 0.77 | KCNN4 (0.51) | KCNN4SMN1; SMN2MAPTALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |