Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990888 | 0.88 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL31411882 | 0.85 | LMNA (0.38) | ALDH1A1L3MBTL1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL6992221 | 0.84 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2HPGDMAPK1KDM4E | |
| SCHEMBL6991944 | 0.83 | KCNN4 (0.48) | ALDH1A1SMN1; SMN2KDM4ENPSR1POLB | |
| SCHEMBL6995107 | 0.82 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HPGDMAPK1KDM4E | |
| SCHEMBL6989440 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4ENPSR1TSHR | |
| SCHEMBL31411665 | 0.81 | KCNN4 (0.42) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL31411601 | 0.81 | CNR2 (0.36) | ALDH1A1SMN1; SMN2HPGDMAPK1KDM4E | |
| SCHEMBL31411767 | 0.81 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL31411715 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |