Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996615 | 0.90 | GSK3A (0.53) | ALDH1A1LMNASMN1; SMN2GSK3AGSK3B | |
| SCHEMBL6991944 | 0.89 | KCNN4 (0.48) | ALDH1A1LMNASMN1; SMN2NPSR1GSK3A | |
| SCHEMBL6991542 | 0.85 | PAX8 (0.59) | ALDH1A1LMNASMN1; SMN2NPSR1KDM4E | |
| SCHEMBL6996093 | 0.85 | GSK3A (0.51) | ALDH1A1LMNASMN1; SMN2GSK3AGSK3B | |
| SCHEMBL6992255 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2NPSR1KMT2A | |
| SCHEMBL7462849 | 0.82 | GSK3A (0.50) | ALDH1A1LMNAGSK3AGSK3BKMT2A | |
| SCHEMBL6990888 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2NPSR1KCNN4KDM4E | |
| Hydrochloric Acid SCHEMBL6998534 | 0.81 | GSK3A (0.49) | ALDH1A1LMNAGSK3AGSK3BKMT2A | |
| SCHEMBL6996076 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2NPSR1KCNN4 | |
| Hydrochloric Acid SCHEMBL6990846 | 0.81 | GSK3A (0.45) | ALDH1A1LMNASMN1; SMN2NPSR1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6274619-B1 | FUSED AMIDINO TYPE COMPOUNDS SUCH AS 4-(N-BUTYLCARBAMOYLMETHYLIDENE)-2-AMIDINO-4,5,6,7-TETRAHYDROBE NZO(B)THIOPHENE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |