Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411660 | 0.89 | LMNA (0.52) | SMN1; SMN2POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411699 | 0.85 | POLB (0.65) | SMN1; SMN2POLBALDH1A1KDM4EALOX15 | |
| SCHEMBL31411613 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL21972975 | 0.80 | ALDH1A1 (0.64) | SMN1; SMN2POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29978554 | 0.80 | ALDH1A1 (0.64) | SMN1; SMN2POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411771 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL25920701 | 0.79 | POLB (0.67) | SMN1; SMN2POLBALDH1A1KDM4EALOX15 | |
| SCHEMBL8551997 | 0.79 | POLB (0.70) | SMN1; SMN2POLBALDH1A1KDM4EALOX15 | |
| SCHEMBL31411648 | 0.78 | MAPT (0.41) | SMN1; SMN2POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411619 | 0.78 | ESR1 (0.42) | SMN1; SMN2POLBALDH1A1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |