Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411699 | 0.91 | POLB (0.65) | POLBSMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL31411647 | 0.85 | LMNA (0.50) | POLBMAPTALDH1A1LMNANPY5R | |
| SCHEMBL31411536 | 0.81 | GSK3B (0.56) | POLBSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL24233398 | 0.80 | CRHR1 (0.45) | POLBSMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL31411575 | 0.78 | SMN1; SMN2 (0.54) | POLBSMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL31411623 | 0.78 | POLB (0.51) | POLBSMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL31411738 | 0.78 | POLB (0.51) | POLBSMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL31411631 | 0.77 | ALDH1A1 (0.56) | POLBSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL31411693 | 0.77 | POLB (0.50) | POLBSMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL8551997 | 0.76 | POLB (0.70) | POLBSMN1; SMN2MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |