Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALPL | P05186 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412631 | 0.81 | HCAR2 (0.41) | RAB9AHCAR2ALDH1A1LRRK2MAPK1 | |
| SCHEMBL6822516 | 0.80 | RAB9A (0.69) | RAB9AMAPTALDH1A1MAPK1MAP2K4 | |
| SCHEMBL5317383 | 0.76 | HDAC6 (0.56) | RAB9AMAPTALDH1A1MAPK1MAP2K4 | |
| SCHEMBL16116177 | 0.73 | CCNC (0.55) | HCAR2GPR35WNT3AHDAC4 | |
| SCHEMBL5937211 | 0.73 | RAB9A (0.49) | RAB9AMAPTALDH1A1MAPK1MAP2K4 | |
| SCHEMBL31412648 | 0.73 | KDM4C (0.38) | RAB9AMAPTALDH1A1LRRK2MAPK1 | |
| SCHEMBL11071707 | 0.72 | RAB9A (0.51) | RAB9AMAPTALDH1A1MAPK1MAP2K4 | |
| SCHEMBL6821694 | 0.69 | RAB9A (0.44) | RAB9AHCAR2MAPTALDH1A1MAP2K4 | |
| SCHEMBL31412652 | 0.68 | TP53 (0.65) | SMN1; SMN2KDM4EALPL | |
| SCHEMBL4638325 | 0.68 | RAB9A (0.70) | RAB9AMAPTALDH1A1MAPK1MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025045746-A1 | PYRAZOLE DERIVATIVES AS SARM1 INHIBITORS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-03-06 | — | — | WO | disclosed |