Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.48 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822516 | 0.85 | RAB9A (0.69) | HDAC6RAB9AMAPK1MAP2K4MAPK6 | |
| SCHEMBL5317300 | 0.81 | HDAC6 (0.54) | HDAC6RAB9AMAPK1ALDH1A1MAPT | |
| SCHEMBL5937211 | 0.80 | RAB9A (0.49) | HDAC6RAB9AMAPK1MAP2K4MAPK6 | |
| SCHEMBL14705874 | 0.77 | HAO1 (0.49) | HDAC6MAPK1MAP2K4MAPK6CA12 | |
| SCHEMBL6821694 | 0.76 | RAB9A (0.44) | HDAC6RAB9AMAP2K4ALPLALDH1A1 | |
| SCHEMBL31412684 | 0.76 | RAB9A (0.48) | HDAC6RAB9AMAPK1MAP2K4MAPK6 | |
| SCHEMBL25210468 | 0.75 | ALDH1A1 (0.47) | HDAC6MAP2K4ALPLALDH1A1HAO2 | |
| SCHEMBL23294515 | 0.75 | HAO1 (0.48) | MAPK1MAP2K4MAPK6CA12ALPL | |
| SCHEMBL4721643 | 0.74 | MAPK14 (0.46) | BCL2L1BADDHODHSMN1; SMN2MAPK13 | |
| SCHEMBL19806684 | 0.74 | RAB9A (0.59) | HDAC6RAB9AMAPK1MAP2K4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079086-A1 | PYRAZOLOALKYL SUBSTITUTED IMIDAZO RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-12 | — | — | WO | disclosed |