Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAP2K4 | P45985 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.42 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822516 | 0.83 | RAB9A (0.69) | RAB9AMAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL5317383 | 0.73 | HDAC6 (0.56) | RAB9AMAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL6821694 | 0.72 | RAB9A (0.44) | RAB9AMAP2K4MAPTMEN1LMNA | |
| SCHEMBL31412684 | 0.72 | RAB9A (0.48) | RAB9AMAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL4638325 | 0.71 | RAB9A (0.70) | RAB9AMAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL5937211 | 0.70 | RAB9A (0.49) | RAB9AMAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL28306041 | 0.69 | HSD17B10 (0.45) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL28742838 | 0.69 | RAB9A (0.48) | RAB9AMAPTMEN1LMNAPKM | |
| SCHEMBL11074145 | 0.69 | RAB9A (0.48) | RAB9AMAPTMEN1LMNAKMT2A | |
| SCHEMBL23294383 | 0.68 | PIN1 (0.47) | RAB9AMAP2K4MAPK1MAPKAPK3MAPK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112623-A2 | 3-Aryl-5-pyrazole-carboxylic-acid derivatives, their preparation and pharmaceutical compositions | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |