Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638325 | 0.86 | RAB9A (0.70) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5317383 | 0.85 | HDAC6 (0.56) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11071707 | 0.83 | RAB9A (0.51) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL27321802 | 0.81 | RAB9A (0.63) | RAB9ALMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5937211 | 0.81 | RAB9A (0.49) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL31412684 | 0.80 | RAB9A (0.48) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8842823 | 0.80 | RAB9A (0.50) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL3491623 | 0.80 | RAB9A (0.50) | RAB9ALMNAMAPTMEN1KMT2A | |
| SCHEMBL17966223 | 0.80 | ALDH1A1 (0.59) | RAB9ALMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL28742838 | 0.80 | RAB9A (0.48) | RAB9ALMNAMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209878-B | Cannabinoid receptor light-operated ligand and preparation method and application thereof | 上海科技大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112209878-A | Cannabinoid receptor light-operated ligand and preparation method and application thereof | 上海科技大学 | 2021-01-12 | — | — | CN | disclosed |
| CN-103596567-B | Pyrazole derivatives | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-16 | — | — | CN | disclosed |
| EP-2717873-B1 | PYRAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2015-07-15 | — | — | EP | disclosed |
| US-9073911-B2 | Pyrazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2015-07-07 | — | — | US | disclosed |
| EP-2717873-A1 | PYRAZOLE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| CN-103596567-A | Pyrazole derivatives | HOFFMANN LA ROCHE | 2014-02-19 | — | — | CN | disclosed |
| US-20120316172-A1 | PYRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-12-13 | — | — | US | disclosed |
| WO-2012168260-A1 | PYRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-12-13 | — | — | WO | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316172-A1 | PYRAZOLE DERIVATIVES | TAAR1, TAAR5, NPY1R | RAB9A 1480/4885LMNA 3742/4885MAPT 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.