SCHEMBL3141297

SCHEMBL3141297

O=S(=O)(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.Sc1cccc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.33
PTGS1 P23219 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
BCL2 P10415 1/20 0.31
BCL2L1 Q07817 1/20 0.31
KLRK1 P26718 1/20 0.31
MICA Q29983 1/20 0.31
RAET1L Q5VY80 1/20 0.31
FGFR1 P11362 1/20 0.30
SRC P12931 1/20 0.30
FGFR2 P21802 1/20 0.30
FGFR4 P22455 1/20 0.30
FGFR3 P22607 1/20 0.30
ARF6 P62330 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1089301 1.00 PTGS2 (0.33) PTGS2PTGS1TP53MAPTADORA2A
SCHEMBL3139727 0.99 PTGS2 (0.34) PTGS2PTGS1TP53MAPTADORA2A
SCHEMBL3136046 0.89 USP7 (0.35) CA1CA2
SCHEMBL3136273 0.89 MAPT (0.34) TP53MAPT
SCHEMBL3130364 0.89 ENPP1 (0.36) PTGS2PTGS1CA1CA2
SCHEMBL3126297 0.89 MAPT (0.34) TP53MAPT
SCHEMBL3139678 0.89 ENPP1 (0.36) PTGS2PTGS1CA1CA2
SCHEMBL1089839 0.88 ENPP1 (0.38) PTGS2PTGS1CA1CA2
SCHEMBL3132992 0.88 ENPP1 (0.38) PTGS2PTGS1CA1CA2
SCHEMBL3144267 0.88 MAPT (0.35) TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed