Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297447 | 0.81 | ALDH1A1 (0.38) | LMNAPKMALDH1A1POLBRECQL | |
| SCHEMBL13160340 | 0.78 | ALDH1A1 (0.49) | LMNAALDH1A1POLBRECQLL3MBTL1 | |
| SCHEMBL16420399 | 0.78 | CYP2C19 (0.51) | LMNAALDH1A1CYP2C19 | |
| SCHEMBL31403471 | 0.76 | DNM1 (0.38) | LMNAPKMALDH1A1POLBRECQL | |
| SCHEMBL30753853 | 0.75 | KMT2A (0.45) | LMNAPKML3MBTL1 | |
| SCHEMBL30753921 | 0.74 | LMNA (0.37) | LMNAPKMALDH1A1POLBRECQL | |
| SCHEMBL2603259 | 0.74 | KMT2A (0.42) | LMNAPKMALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL14984936 | 0.74 | MEN1 (0.47) | MCHR1HSD17B10HRH4 | |
| SCHEMBL8980164 | 0.74 | MEN1 (0.47) | MCHR1HSD17B10HRH4 | |
| SCHEMBL27748816 | 0.74 | EPHX2 (0.44) | LMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630656-A | Heterocyclic compounds for inducing cleavage of mutant KRAS proteins | 安斯泰来制药株式会社 | 2025-03-14 | — | — | CN | disclosed |